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Introduction The assessment of hormonal
2019-05-10
Introduction The assessment of hormonal receptor (HR) and human epidermal growth factor receptor-2 (HER2) status by immunohistochemistry (IHC) groups breast cancer into three major subtypes: 1) luminal-like subtype (HR positive/HER2 negative); 2) HER2 subtype (HER2 positive and HR negative/positive
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The regular meridians are distributed symmetrically on the l
2019-05-09
The 12 regular meridians are distributed symmetrically on the left and right sides of the body, and run along their fixed courses. The temperature of paired bilateral acupoints shows symmetry and correlation to the left and right sides. One member of our research group, Bing Xiong, compared the skin
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In this study the distribution of LPs was also analyzed
2019-05-09
In this study, the distribution of LPs was also analyzed. Similar to previously published data, there was a tendency that vLPs were more frequently observed in patients with ICM than in patients with NICM. However, the total number of those abnormal ventricular electrograms was less documented than
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We herein report a patient with dMMR
2019-05-09
We herein report a patient with dMMR and MSI-H metastatic gastric cancer who prostaglandin receptor responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1
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The goals are set the targets laid out
2019-05-09
The goals are set; the targets laid out. The fighting is over. In just over a week\'s time, heads of state worldwide will commit to the , with its 17 Sustainable Development Goals (SDGs) and 169 associated targets. Country representatives will resolve to do everything from ending poverty and hunger
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I received a grant from The
2019-05-09
I received a grant from The Kendeda Fund to write and promote my book, , on which this comment is based. I thank Richard King (Chatham House, London, UK) for data assistance, Christian Guthier (All is Possible, Oxford, UK) for graphic design, and Sarah Cornell (Stockholm Resilience Centre, Stockholm
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El recorrido inicia con una revisi n de
2019-05-09
El recorrido inicia con una revisión de las colaboraciones de Paz en la revista entre la que destaca la del número 197, de marzo de 1951. El famoso de David Rousset en torno MG 262 manufacturer los campos de concentración en la . Lo que marcaría la ruptura de Paz con la izquierda stalinista latino
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br Substantial gains have been made globally for many
2019-05-08
Substantial gains have been made globally for many of the health targets, but progress in the improvement of health has been unequal with respect to the most vulnerable populations, and major discrepancies persist across regions and socioeconomic status. Maternal immunisation is a unique opportu
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Macrophages in bone metastasis main outstanding questions br
2019-05-08
Macrophages in bone metastasis – main outstanding questions: Conflict of interest statement Acknowledgements IV was supported by a generous grant from Weston Park Hospital Cancer Charity, Sheffield, UK. Introduction In recent years there has been increasing interest in the role of bone-ta
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The canonical or catenin dependent Wnt
2019-05-08
The canonical, or β-catenin dependent, Wnt signaling pathway is critical for the regulation of osteoblast proliferation and survival [95]. Soluble inhibitors of the canonical Wnt pathway such as Dickkopf (DKK1), produced by OBL, and sclerostin, from osteocytes, play important roles in the regulation
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Vuelve a aparecer aqu la ntima satisfacci n de un
2019-05-08
Vuelve Puromycin aparecer aquí la íntima satisfacción de un Aub cuyas obras, por expeditivas que sean —dos semanas para elaborar toda una exposición— y mediocres que puedan parecer, levantan pasiones entre los entendidos en arte porque en buena medida es a ellos, capaces de mutar la arena en oro y l
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This relationship will be complicated the prevalence of mala
2019-05-08
This relationship will be complicated: the prevalence of malaria infection in non-pregnant adults is lower than that for children within the same setting, a finding probably related to the differing levels of immunity in the adult and child populations. Since immunity depends on previous exposure an
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Al ser verdad lo anterior no lo es menos
2019-05-08
Al ser verdad lo anterior, no lo es menos que la cultura asentada en tiempos coloniales, a diferencia de la que llegó en los primeros tiempos de la conquista, respondía a la relativa ignorancia del mundo clásico en España, sobre todo del griego. Fue el país donde más se leyeron sus autores en traduc
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HLA DR resulted highly expressed in the surface of immature
2019-05-08
HLA-DR resulted highly expressed in the surface of immature DC (iDC) as well as in mature DC (48 h-DC) in both groups; this is possibly due to the chronic infection as previously observed in monocytes-derived DC from HIV+[17]. As expected, maturation and activation markers - CD40, CD80, CD83 and CD8
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Sustained AT Fig b B was induced
2019-05-08
Sustained AT2 (Fig. 1b(B)) was induced during pacing from the coronary sinus. The 3D activation map and the entrainment mapping including PPI from the CTI identified AT2 as a macroreentrant tachycardia circling counter-clockwise around the TA. AT2 was eliminated by CTI ablation. Sustained AT3 (Fig.
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