• In primary diagnosis IKZF status was

  2019-06-06

  

  In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19

• To date over mutations in

  2019-06-05

  

  To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [

• br Materials and methods br Results br Discussion

  2019-06-05

  

  Materials and methods Results Discussion Conclusions Conflict of interest Acknowledgments Introduction Circumferential how to calculate molarity (PV) isolation has been accepted by a consensus as the strategy for the treatment of atrial fibrillation (AF) using catheter ablation

• p53 tumor suppressor Detailed data were available in Kilifi

  2019-06-05

  

  Detailed data were available in Kilifi not only on carriage of vaccine types of pneumococci, but also on receipt of vaccine by the individuals in the study, and the overall vaccine coverage in the p53 tumor suppressor was also known. The data suggest that vaccine coverage of around two-thirds of chi

• Interim measures however are not nearly enough

  2019-06-05

  

  Interim measures, however, are not nearly enough. A massive expansion of the blood donor pool is needed, but scaling up blood donation in the low-resource world is no easy task. WHO has long advocated a set of interventions to fortify a nation\'s blood supply, but countries will have difficulty solv

• Este nuevo orden de lo

  2019-06-05

  

  Este nuevo orden de “lo latinoamericano” ha afectado también en el estatuto de otras disciplinas, entre ellas literatura comparada, estudios étnicos, latinidad norteamericana, Caribe, sociología, pensamiento teológico y hasta en una nueva dimensión hemisférica de los American Studies. Son muchas las

• In the management of BrS patients

  2019-06-05

  

  In the management of BrS patients, it is important to avoid or treat certain drugs or circumstances such as a febrile state, electrolyte disturbances (hyperkalemia and hypercalcemia), and the use of class Ia/Ic antiarrhythmic drugs, vagotonic agents, beta-adrenergic antagonists, tricyclic antidepres

• The first variant in the non spine topic

  2019-06-05

  

  The first variant in the non-spine topic describes a patient with an excellent performance status, a favorable life expectancy, and an asymptomatic mineralocorticoid receptor lesion which does not pose an obvious risk for pathologic fracture. While the authors acknowledge that research has begun to

• br Results and discussion br Authorship contributions br Con

  2019-06-01

  

  Results and discussion Authorship contributions Conflict of interest Acknowledgments This work is supported by grants from the United States National Institutes of Health/National Cancer Institute: R01 CA098472 and R01 CA170334. We thank Dr. Dan Zhang and Andy Awwad for technical assista

• br Genetic basis Similar to other arrhythmia syndromes Bruga

  2019-06-01

  

  Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the

• br Mechanisms of ventricular fibrillation electrical storm i

  2019-06-01

  

  Mechanisms of ventricular fibrillation/electrical storm in the Brugada syndrome patients One of the most consistent features of BrS is that premature ventricular contraction (PVC), which triggers VF, is almost always short-coupling [3,4]. An interesting phenomenon is that many of the VF episodes

• The pathophysiology underlying ONJ is unclear Decreased bone

  2019-06-01

  

  The pathophysiology underlying ONJ is unclear. Decreased bone remodeling induced by bisphosphonates or inhibition of osteoclast function, which interferes with healing of the microfractures and trauma occurring after dental extraction, have been hypothesized as potential mechanisms for ONJ, but thes

• glucose assay According to the labeling of dabigatran in Jap

  2019-06-01

  

  According to the labeling of dabigatran in Japan, patients to be considered for the prescription of the lower dose of 220mg/day are as follows: (1) aged ≥70 years, (2) with moderate renal impairment (ClCr 30–50mL/min), (3) concomitant use of a p-glycoprotein inhibitor, and (4) history of hemorrhage

• Natural Product Library Mismo fen meno se observa

  2019-06-01

  

  Mismo fenómeno se observa en El Museo Mexicano, publicación ciertamente exitosa y donde se dieron cita los escritores más sobresalientes de la literatura mexicana decimonónica entre los años 1843 hasta 1846. El epígrafe que remata la portada constituye, en términos programáticos, todo una declaració

• Antes de consultar aquellas fuentes cr tico te ricas

  2019-06-01

  

  Antes de consultar aquellas fuentes crítico-teóricas, conviene considerar por sí solo. En este breve libro, un narrador recorre el mismo camino en distintas ocasiones, nuclear receptor veces a solas y otras acompañado por su bella y amada pareja. El camino de Galta en la India, que conduce a un tem

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